Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis

Wang, Feng, Kong, Lingchi, Wang, Wenbo, Shi, Li, Wang, Mengwei, Chai, Yimin, Xu, Jia, Kang, Qinglin

Abstract Background Both advanced glycation end products (AGEs) and AGE-mediated M1 macrophage polarization contribute to bone marrow mesenchymal stem cell (...