OP0215 SPATIAL TRANSCRIPTOMICS OF SKIN BIOPSIES FROM VERY EARLY SYSTEMIC SCLEROSIS UNVEILS EARLY DRIVERS OF SKIN FIBROSIS WITHIN THE EPIDERMIS

<h2>Abstract</h2><h3>Background:</h3> Skin homeostasis is driven by a finely tuned balance between epidermis and the dermis. The perivascular inflammation an...