Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants

Abhinay Gontu, Sougat Misra, Shubhada K. Chothe, Santhamani Ramasamy, Padmaja Jakka, Maurice Byukusenge, Lindsey LaBella, Meera Surendran Nair

SARS-CoV-2 continues to evolve and evade vaccine immunity necessitating vaccines that offer broad protection across variants. Conventional mRNA vaccines face...