GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone

Joonho Suh, Na-Kyung Kim, Seung‐Hoon Lee, Je‐Hyun Eom, Youngkyun Lee, Joo‐Cheol Park, Kyung Mi Woo, Jeong‐Hwa Baek

Growth and differentiation factor 11 (GDF11) and myostatin (MSTN) are closely related transforming growth factor β (TGF-β) family members, but their biologic...