Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na + ,K + -ATPase Blocks HIV-1 Infection

Silvia Agostini, Hashim Ali, Chiara Vardabasso, Antonio Fittipaldi, Ennio Tasciotti, Anna Cereseto, Antonella Bugatti, Marco Rusnati

Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In ...