Insulin-Like Growth Factor I (IGF-I) and Cyclic Adenosine 3′,5′-Monophosphate Regulate IGF-Binding Protein-3 Gene Expression by Transcriptional and Posttranscriptional Mechanisms in Mammary Epithelial Cells1

Insulin-like growth factor I (IGF-I) is a potent mitogen for both normal and transformed mammary epithelial cells (MEC), and IGF-binding protein-3 (IGFBP-3) ...