article · 2013
An R132H Mutation in Isocitrate Dehydrogenase 1 Enhances p21 Expression and Inhibits Phosphorylation of Retinoblastoma Protein in Glioma Cells
Cytosolic isocitrate dehydrogenase 1 (IDH1) with an R132H mutation in brain tumors loses its enzymatic activity for catalyzing isocitrate to α-ketoglutarate ...
11 citationsDOI: https://doi.org/10.2176/nmc.oa2012-0409Open accessPDF reported by metadataFull text reported by metadata