Platelet 12-lipoxygenase Arg261Gln polymorphism: functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms

Yongli Guo, Xuemei Zhang, Wen Tan, Xiaoping Miao, Tong Sun, Dan Zhao, Dongxin Lin

These observations suggest that inherited polymorphisms in arachidonic acid-metabolizing enzymes, which result in heightened gene expression or enzymatic act...