Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway

Jianxin Dou, Huating Li, Xiaojing Ma, Mingliang Zhang, Qichen Fang, Meiyun Nie, Yuqian Bao, Weiping Jia

Our study demonstrates that OCN has an endothelial-protective effect in atherosclerosis through mediating the PI3K/Akt/eNOS signaling pathway.