Cerebral Arterial Pulsation Drives Paravascular CSF–Interstitial Fluid Exchange in the Murine Brain

Jeffrey J. Iliff, Minghuan Wang, Douglas Zeppenfeld, Arun Venkataraman, Benjamin A. Plog, Yonghong Liao, Rashid Deane, Maiken Nedergaard

CSF from the subarachnoid space moves rapidly into the brain along paravascular routes surrounding penetrating cerebral arteries, exchanging with brain inter...