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article · 2013

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy

A hypoxic microenvironment induces resistance to alkylating agents by activating targets in the mammalian target of rapamycin (mTOR) pathway. The molecular m...

196 citationsDOI: https://doi.org/10.1073/pnas.1314469111Open accessPDF reported by metadata
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy