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article · 1991

Biologically active taxol analogs with deleted A-ring side chain substituents and variable C-2' configurations

Taxol, a potent inhibitor of cell replication, enhances the assembly of tubulin into stable microtubules and promotes the formation of microtubule bundles in...

182 citationsDOI: https://doi.org/10.1021/jm00107a042
Biologically active taxol analogs with deleted A-ring side chain substituents and variable C-2' configurations