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article · 2011

Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

A novel approach has been developed for the isolation and maturation of human antibodies that replicates key features of the adaptive immune system by coupli...

103 citationsDOI: https://doi.org/10.1073/pnas.1114010108Open accessPDF reported by metadataFull text reported by metadata
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies