Efficiency of Excision of 8-Oxo-guanine within DNA Clustered Damage by XRS5 Nuclear Extracts and Purified Human OGG1 Protein

A major DNA lesion is the strongly mutagenic 8-oxo-7,8-dihydroguanine (8-oxoG) base, formed by oxidative attack at guanine and which leads to a high level of...