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article · 2012

ACS Chemical Neuroscience Molecule Spotlight on Begacestat (GSI-953)

A "second generation" γ-secretase, Begacestat (GSI-953), which is more selective against Notch-signaling, has shown promise in recent Phase I clinical trials...

35 citationsDOI: https://doi.org/10.1021/cn200124uOpen accessPDF reported by metadataFull text reported by metadata
ACS Chemical Neuroscience Molecule Spotlight on Begacestat (GSI-953)