Involvement of the Na+-independent Cl–/HCO3–exchange (AE) isoform in the compensation of myocardial Na+/H+isoform 1 hyperactivity in spontaneously hypertensive rats.

Enhanced activity of Na+/H+ isoform 1 (NHE-1) and the Na+-independent Cl-/HCO3- exchange (AE) is a feature of the hypertrophied myocardium in spontaneously h...