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article · 2013

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy

Somatic hypermutation in B cells is initiated by activation-induced cytidine deaminase-catalyzed C→U deamination at immunoglobulin variable regions. Here we ...

49 citationsDOI: https://doi.org/10.1038/ncomms2823Open accessPDF reported by metadataFull text reported by metadata
GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy