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article · 2011

New domino radical synthesis of aminoalcohols promoted by TiCl4–Zn/t-BuOOH system: selective hydroxyalkylation of amines in alcohol or in cyclic ether cosolvents

We report a new and fast domino synthesis of aminoalcohols under mild conditions. The free-radical reaction of aliphatic and aromatic amines with alcohol cos...

15 citationsDOI: https://doi.org/10.1039/c1ob05191a
New domino radical synthesis of aminoalcohols promoted by TiCl4–Zn/t-BuOOH system: selective hydroxyalkylation of amines in alcohol or in cyclic ether cosolvents