IL-12 gene therapy protects mice in lethal Klebsiella pneumonia

M J Greenberger, S L Kunkel, Robert M. Strieter, Nicholas W. Lukacs, Jonathan L. Bramson, Jack Gauldie, Felicia L. Graham, Mary Hitt

IL-12 is a proinflammatory cytokine that has recently been shown to have beneficial effects in the setting of acquired host immunity. To determine the role o...