article · 2009
A preclinical pharmacokinetic and pharmacodynamic approach to determine a dose of spironolactone for treatment of congestive heart failure in dog
Fifteen Beagle dogs were used to describe the anti-aldosterone effect of spironolactone (0, 0.8, 2 and 8 mg/kg) in a hyperaldosteronism model. The magnitude ...
22 citationsDOI: https://doi.org/10.1111/j.1365-2885.2009.01130.xOpen accessPDF reported by metadataFull text reported by metadata